Choosing the right audio interface for Reaper can unlock lower latency, cleaner recordings, and a more efficient workflow. This guide highlights five reliable interfaces that work well with Reaper on Windows and macOS, offering solid preamps, versatile I/O, and straightforward setup. Whether you’re recording vocals, guitar, or podcasts, these picks balance performance, price, and compatibility.
| Product | Brand | Key Benefit |
|---|---|---|
| Focusrite Scarlett Solo 3rd Gen | Focusrite | Bright preamps, Air mode, 24-bit/192kHz |
| Universal Audio Volt 1 | Universal Audio | Classic UA sound, 24-bit/192kHz, LUNA integration |
| Mackie Onyx Producer 2×2 | Mackie | High-headroom preamps, MIDI I/O, solid build |
| PreSonus AudioBox 96 25th Anniversary | PreSonus | Two preamps, MIDI I/O, compact and portable |
| PreSonus AudioBox GO | PreSonus | Ultra-portable USB-C, Studio One Prime, bus-powered |
These selections are chosen for users who want reliable ASIO/Core Audio performance with Reaper, clear monitoring, and enough inputs to record multiple sources. Each option offers driver support and software that can streamline your workflow, from classic analog emulation to modern digital processing.
Focusrite Scarlett Solo 3rd Gen

The Focusrite Scarlett Solo 3rd Gen offers two key advantages for Reaper users: high-headroom mic pre-amps and the Air mode for brighter recordings on acoustic instruments. The Solo 3rd Gen model provides a single instrument input and a mic input with Gain Halos to avoid clipping, plus 24-bit/192kHz conversion for studio-quality sound. For singers and composers using Reaper, this interface emphasizes clean capture with straightforward monitoring, making it a reliable starter or upgrade option for home studios.
In practice, its simple layout reduces setup time in Reaper, and the low-latency driver performance helps maintain tight overdubs. The integration of high-quality preamps and the Air mode can yield a more open vocal take, which you can further shape in Reaper’s plugins. While it’s a single-channel focus, its clarity and headroom suit solo projects, podcasting, and guitar recording well.
Universal Audio Volt 1 USB

The Universal Audio Volt 1 brings UA’s classic preamp timbre into a compact, USB-C interface. With up to 24-bit/192 kHz conversion and high-quality converters, it’s a strong choice for Reaper users seeking warm, musical detail on vocals and guitars. UA’s ecosystem and plug-ins can complement Reaper projects, offering polished tones right out of the box. While Volt 1 emphasizes simplicity, it does not skimp on build and audio fidelity, making it appealing for home studios aiming for pro-grade results in a small footprint.
Latency performance, driver stability, and the ability to run UAD-powered effects inside Reaper can influence your decision. For users who value fat, characterful preamps and minimal driver headaches, Volt 1 provides a reliable path to high-quality tracking and mixing with Reaper’s flexible routing and automation capabilities.
Mackie Onyx Producer 2×2

The Mackie Onyx Producer 2×2 combines two boutique-quality Onyx mic preamps with a robust MIDI I/O setup. For Reaper users, the two high-quality pres provide clean, transparent capture with ample headroom for dynamic vocalists and instruments. The mix control and monitor routing are straightforward, enabling easy latency management and stereo monitoring. This interface is well-suited to small-to-medium home studios that require reliable DAW integration alongside occasional MIDI sequencing and external gear control.
With 24-bit/192kHz capabilities, sturdy construction, and solid drivers, it’s a fit for sessions where consistent performance across both recording and playback matters. If your workflow includes external synths or MIDI devices, the inclusion of MIDI I/O helps keep everything synchronized in Reaper without extra adapters or complexity.
PreSonus AudioBox 96 25th Anniversary

The AudioBox 96 25th Anniversary edition emphasizes value and portability for Reaper users. It features two Class-A mic preamps, two high-headroom instrument inputs, and MIDI I/O, making it versatile for voice work, guitar or bass, and external gear. The inclusion of Studio One Artist is a bonus for users exploring a broader Studio ecosystem, yet Reaper remains fully compatible, giving users an affordable route to solid audio capture and monitoring. The compact form factor also supports mobile recording setups or small home studios where space is at a premium.
Sound quality from the preamps and the converters keeps your recordings faithful to the original performance. For those who value bundle software, this model provides practical tools to get started, while still offering dependable compatibility with Reaper for editing, comping, and mixing workflows.
PreSonus AudioBox GO

The AudioBox GO emphasizes portability and modern connectivity with USB-C power and bus-powered operation. It’s ideal for mobile Reaper users who track on the go or in small project studios. With Studio One Prime and the Studio Magic software bundle, users gain a jump-start on new sounds and workflows, while Reaper remains the primary DAW for recording and editing. The interface’s compact design does not compromise essential inputs, making it a solid choice for guitar, voice, and podcast recordings in flexible environments.
For those prioritizing minimal setup and USB-C compatibility, AudioBox GO balances convenience with reliable audio performance, making it suitable for quick demos, travel sessions, and home setups that require dependable, plug-and-play operation with Reaper.
Buying Guide: Key Considerations For Reaper Users
When selecting an audio interface for Reaper, consider these core factors to ensure a smooth, productive workflow:
- Compatibility and drivers: Ensure the interface offers stable ASIO (Windows) or Core Audio (macOS) drivers, plus regular updates.
- Latency and monitoring: Look for low-latency monitoring with direct monitoring options and a direct monitor mix for real-time performance without DSP-based latency in Reaper.
- Preamps and gain: Evaluate mic preamp quality, headroom, and phantom power if you plan to record condensers or loud sources.
- Input/Output configuration: Match the number and type of inputs (XLR, instrument, line, MIDI) to your typical setup (vocals, guitar, podcast, interfaces with external gear).
- Bus power vs. external power: USB-powered interfaces are convenient; others may require a power supply for higher headroom or additional features.
- Software bundles and ecosystem: Some interfaces include DAWs or plugins that can complement Reaper workflows, though Reaper itself remains the center of production.
- Build quality and portability: A sturdy chassis and compact size are advantageous for mobile setups or small home studios.
- Future expansion: If you anticipate adding more gear, consider interfaces with MIDI I/O or additional outputs.
In practice, your choice depends on the balance you want between portability, input count, and sonic character. For classic, clean recordings with recognizable warmth, models from Focusrite and Universal Audio offer strong preamps and reliable drivers. If you prioritize portability and budget, PreSonus options deliver compact form factors with essential I/O and strong software bundles. Regardless of the pick, confirm that Reaper recognizes the device and that your latency settings align with your monitoring needs for efficient tracking and mixing sessions.